South Central

PREP Region South Central

South Central Pennsylvania is the third-largest region in the state by both population and number of businesses, consisting of eight counties along Pennsylvania’s southern border with Maryland. Anchored by Lancaster, York, Gettysburg, Hershey and Harrisburg, the region boasts a population of nearly 2 million people. Its strengths are similar to those of Pennsylvania as a whole: a location convenient to markets and a quality workforce. Strategically located on a network of interstate highways, rail lines with intermodal facilities, and a growing air freight industry — with convenient passenger flights at Harrisburg International Airport — the region serves as the transportation crossroads of the Mid-Atlantic.

Top Industries

  • Advanced Manufacturing
  • Agriculture & Food Processing
  • Business and Financial Services
  • Education & Health Care
  • Logistics

Regional Employers

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